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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 19 May 2025 Vol. No. 14 ; Issue No.683
Publications

1.Rai P, Mahajan K, Janu AK (2025). Dedifferentiated chondrosarcoma with multiple synchronous osteosarcomas in a young female patient. Radiology: Imaging Cancer. 7(3):e240522.

Thesis
Zaid Muneef Shaikh. 2025. Molecular studies on chemoprevention using Polymeric Black-tea Polyphenols (PBP’s) on experimental lung carcinogenesis.(LIFE09201804016) (Guide: Dr. Manoj Mahimkar)

Site of the Week

MedGen organizes information related to human medical genetics, such as attributes of conditions with a genetic contribution

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Interesting Reads

Yau T, Galle PR, Decaens T, Sangro B, Qin S, da Fonseca LG, Karachiwala H, Blanc JF, Park JW, Gane E, Pinter M, Peña AM, Ikeda M, Tai D, Santoro A, Pizarro G, Chiu CF, Schenker M, He A, Chon HJ, Wojcik-Tomaszewska J, Verset G, Wang QQ, Stromko C, Neely J, Singh P, Jimenez Exposito MJ, Kudo M, CheckMate 9DW investigators. Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW) (2025): An open-label, randomised, phase 3 trial. Lancet.

Video of the Week
Hemophagocytic Lymphohisticocytosis( HLH): A Unique Disorder of Immune Regulation and what it may Teach Us about Human Immunology, Interferon Biology and Cancer
Upcoming Events
Workshop on Tobacco Control and Cessation

May 30-31, 2025

At Tata Memorial Hospital, Parel

Conference & Hands-On Workshop: From Reconstruction to Restoration

June 21, 2025

At ACTREC, Tata Memorial Centre, Kharghar , Navi Mumbai

Systematic Review and Meta Analysis Workshop

June 26-28, 2025

At ACTREC, Tata Memorial Centre, Kharghar , Navi Mumbai.

Do You Know?

In 2011, a study introduced the concept of ‘senescence surveillance’, wherein premalignant senescent hepatocytes are cleared through a tumour-antigen-directed immune response.

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Cancer News
Study finds common genetic target may halt breast cancer cell growth

MedicalXpress, 15/05/2025

Researchers focused on an enzyme called polo-like kinase 1 (PLK1), which is found in large amounts in nearly all cancer cells and helps tumors grow...

Study reveals targetable mechanism behind high-risk predisposition gene in pediatric medulloblastoma

EurekAlert, 15/05/2025

MDM2 stops p53 activity by sparking the destruction of the tumor suppressor. When the researchers blocked MDM2, preventing its destruction, active p53 could kill cancerous cells. In mouse models of SHH-medulloblastoma that harbor ELP1 loss, MDM2 inhibition significantly increased survival...

Immune control of metastatic cancer at the edge of the central nervous system

Nature, 14/05/2025

Leptomeningeal metastasis is a deadly consequence of cancer that creates an unusually inflamed environment around the brain and spinal cord. One of the inflammatory signalling molecules found in cerebrospinal fluid, interferon-γ, induces an antitumour immune response through an unexpected...

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